Anabolic steroids can cause cardiovascular disease by blocking the binding of cortisol to the receptor sites and it is this that prevents the breakdown of the muscles while initiating their recovery. The above-mentioned use is beneficial initially but if the use is stopped, the effects backfire. There exist, due to this, abnormal production of male hormones in the body of a male athlete, which in most cases is the scenario with the athletes (Thomas, 2012). This makes the secretion of cortisol and the cortisol receptor sites experience an increase in the adrenal cortex, a situation that becomes dangerous to the athlete that uses the drug as it induces the blood pressure activation. The blood pressure results from the inhibition of uptake of the extraneuronal.
Prolonged use and abuse of the compound AAS have increased chances of developing ruptures in the tendons, within the upper parts of the body. The high risk has been contributed to by the increase in the mass of the skeletal muscle as well as strength and the slow pace of the adaptation process of the connective tissues. Long-term use of the drug AAS, together with the resistance for training in an individual using these have been sighted to be the cause of the stiffness in the tendons (Abuse of anabolic steroids: A dangerous indulgence., n.d.). The use of the compound further results to change in the metabolism of both type one and type three fibers of collagen and hence the rapture experience in the muscles.