Tutorial 1 – Written Assignment (Virtual Experiment)
(Note: This instruction document must be read in conjunction with the assessment
Criteria and Standards given in the learning guide)
Scenario:
NS-009 is a newly developed drug proposed for the treatment of metabolic syndrome.
This virtual experiment is to evaluate the effect of NS-009 on type 2 diabetes. You
are asked to test this drug by conducting an in vivo study using a suitable laboratory
animal model of type 2 diabetes. You are asked to treat the experimental animals orally
with NS-009 (100 mg/kg) for 4 weeks. You are asked to collect blood samples at the
end of 4-week treatment period to measure serum glucose and insulin levels. During
your laboratory investigation, the following raw data is obtained for the experimental
groups of animals after analysing the blood samples:
Healthy animal group (n=6)
Serum biomarker Raw values
Glucose (mg/dL) 102, 100, 98, 111, 109, 105
Insulin (µU/mL) 5, 8, 9, 7, 5, 7
Diabetic animal group (n=6)
Serum biomarker Raw values
Glucose (mg/dL) 214, 230, 239, 228, 240, 225